A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).
نویسندگان
چکیده
References http://genesdev.cshlp.org/content/24/11/1073.full.html#related-urls Article cited in: http://genesdev.cshlp.org/content/24/11/1073.full.html#ref-list-1 This article cites 7 articles, 2 of which can be accessed free at: service Email alerting click here top right corner of the article or Receive free email alerts when new articles cite this article sign up in the box at the Collections Topic (98 articles) Post-transcriptional Control Articles on similar topics can be found in the following collections
منابع مشابه
Implementing a rational and consistent nomenclature for serine/arginine-rich protein splicing factors (SR proteins) in plants.
Growing interest in alternative splicing in plants and the extensive sequencing of new plant genomes necessitate more precise definition and classification of genes coding for splicing factors. SR proteins are a family of RNA binding proteins, which function as essential factors for constitutive and alternative splicing. We propose a unified nomenclature for plant SR proteins, taking into accou...
متن کاملSerine-arginine (SR)-rich splicing factors have an exon-independent function in pre-mRNA splicing.
Two distinct functions have been proposed for the serine-arginine (SR)-rich family of splicing factors. First, SR proteins are essential splicing factors and are thought to function by mediating protein-protein interactions within the intron during spliceosome assembly. Second, SR proteins bind to exonic enhancer sequences and recruit spliceosome components to adjacent introns. The latter activ...
متن کاملAltered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in Mammalian cells lacking topoisomerase I.
DNA topoisomerase I (Topo I) specifically phosphorylates arginine-serine-rich (SR proteins) splicing factors and is potentially involved in pre-mRNA-splicing regulation. Using a Topo I-deficient murine B lymphoma-derived subclone (P388-45/C) selected for its resistance to high dosage of the antitumor drug camptothecin, we show that Topo I depletion results in the hypophosphorylation of SR prote...
متن کاملSerine/arginine-rich splicing factors belong to a class of intrinsically disordered proteins
Serine/arginine-rich (SR) splicing factors play an important role in constitutive and alternative splicing as well as during several steps of RNA metabolism. Despite the wealth of functional information about SR proteins accumulated to-date, structural knowledge about the members of this family is very limited. To gain a better insight into structure-function relationships of SR proteins, we pe...
متن کاملAn SC35-like protein and a novel serine/arginine-rich protein interact with Arabidopsis U1-70K protein.
The U1 small nuclear ribonucleoprotein 70-kDa protein, a U1 small nuclear ribonucleoprotein-specific protein, has been shown to have multiple roles in nuclear precursor mRNA processing in animals. By using the C-terminal arginine-rich region of Arabidopsis U1-70K protein in the yeast two-hybrid system, we have identified an SC35-like (SR33) and a novel plant serine/arginine-rich (SR) protein (S...
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عنوان ژورنال:
- Genes & development
دوره 24 11 شماره
صفحات -
تاریخ انتشار 2010